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Clinics: Mayo Clinic (Rochester, MN) vs. MD Anderson Cancer Center (Houston, TX)

Quick Verdict

Both Mayo Clinic and MD Anderson Cancer Center are excellent choices depending on the specific medical needs. Mayo Clinic is a strong choice for a broad range of specialties and high patient satisfaction, while MD Anderson is the preferred option for comprehensive cancer care, offering extensive clinical trials and telemedicine services. However, insurance coverage should be carefully considered, especially for those in Texas seeking individual ACA plans.

Key features – Side-by-Side

AttributeMayo Clinic (Rochester, MN)MD Anderson Cancer Center (Houston, TX)
Specialty focusCardiology & heart surgery, ear, nose & throat, gastroenterology & GI surgery, neurology & neurosurgery, and pulmonology & lung surgeryComprehensive cancer care, including clinical trials, prevention, screening, and treatment for common and rare cancers. Specialized centers for various cancer types.
Availability of clinical trialsWide range of clinical trials focused on various treatmentsMD Anderson has the world's largest cancer clinical trials program. In 2024, they enrolled 11,000 patients in clinical trials.
Acceptance of insurance plansArrangements with many healthcare insurers; participate in Medicare (original Parts A, B, and D) in Arizona, Florida, Rochester, Minnesota, and all Mayo Clinic Health System locations, but not all Medicare Advantage plans; accept Medicaid and TRICAREMD Anderson is not a participating provider for any Individual insurance plans on or off the marketplace in Texas (i.e., ACA plans). Some individual plans outside of Texas may allow in-network access, but verification with the insurance plan is needed. Plans offering out-of-network benefits may be accepted if they meet MD Anderson's requirements. They are contracted with some Medicare Advantage plans, including certain Blue Cross & Blue Shield of Texas plans and Kelsey-Care Medicare Advantage. Traditional Texas Medicaid is accepted.
Patient satisfaction ratingsOverall rating of 95 out of 100; 96 out of 100 would recommend the hospital to others; consistently high patient experience ratings, including 5-star ratings from CMSHospital patients: 90% rated MD Anderson as a 9 or 10 on a 10-point scale (June 2024-May 2025 data). Hospital patients: 92% would definitely recommend MD Anderson (June 2024-May 2025 data). Outpatient clinics: 94% of patients rated their provider as a 9 or 10 on a 10-point scale (June 2024-May 2025 data). Outpatient clinics: 96% would definitely recommend their provider's office (June 2024-May 2025 data). MD Anderson has a 4.5-star rating with 1,822 reviews.
Waiting times for appointmentsVary; some found it easy to schedule, while others experienced long waits between appointmentsMD Anderson is working to improve access to care and reduce wait times based on patient feedback.
Location and accessibilityRochester, Minnesota, approximately 90 miles south of Minneapolis and St. Paul; connected to nearby hotels and other buildings via climate-controlled pedestrian walkways and skyways; shuttle services between campuses and some hotels; wheelchairs available free of charge; accessible parking, including handicapped-accessible parking, availableLocated in the Texas Medical Center in Houston. Main Building: 1515 Holcombe Blvd, Houston, TX 77030. Multiple locations throughout the Greater Houston area. Accessible via major highways (I-610 and SR-288), METRO bus routes and METRORail. MD Anderson Directions app available for navigation.
Availability of telemedicine servicesNot availableTelehealth is an option for follow-up patients. Most participants in a study expressed high satisfaction with telehealth for breast cancer management.
Expertise and reputation of doctorsReputation for excellence and expertise, attracting referrals for complex cases; many physicians are considered among the best in their specialtiesMD Anderson's physicians are extensively trained specialists. 100% of their surgeons are trained in oncology (compared to 30% in community hospitals). MD Anderson boasts one of the nation's most esteemed faculties.
Use of advanced technology and equipmentAdvanced imaging technology, including 7-tesla MRI scanners and photon-counting CT scanners; dedicated Additive Manufacturing Facility for 3D printing of medical devices; intraoperative MRI for real-time surgical imagingThey use state-of-the-art equipment, instruments, and shared services. The institution has advanced technology like CT scans and MRI equipment. They have the nation's first medical cyclotron. They developed IMRT, a precise radiation therapy technique.
Support services for patients and familiesVariety of support services, including social work, spiritual services, and patient education; respite for families with patients in transplant, Level II nursery, and hematology/oncology units; services to inform patients and caregivers about available amenitiesOffers counseling, nutritional guidance, social work, and spiritual care. They have support groups facilitated by licensed social workers. Patient and Family Advisory Councils provide input on care delivery. myCancerConnection offers one-on-one support.
Hospital affiliation and integrationIntegrated medical center comprising Saint Marys Campus and Methodist Campus; "single integrated hospital practice"MD Anderson collaborates with community hospitals and health systems nationwide through the MD Anderson Cancer Network. They have partner members, certified members, associate members, and affiliates.
Cost of treatment and payment optionsOnline payments, mail, in-person, and phone; accept Discover, MasterCard, American Express, Visa, Apple Pay, Google Pay, and ACH bank account payments; payment plans and financial assistance are available to those who qualifyMD Anderson arranges special agreements for some patients who may not be fully covered. They provided $346 million in uncompensated care to uninsured or underinsured Texans in Fiscal Year 2024.

Overall Comparison

Mayo Clinic: 95/100 patient rating, 96/100 recommendation rate. MD Anderson: 90% hospital patients rated 9 or 10, 92% would recommend; 94% outpatient rated 9 or 10, 96% would recommend.

Pros and Cons

Mayo Clinic (Rochester, MN)

Pros:
  • Wide range of specialties
  • Conducts a wide range of clinical trials
  • Accepts a variety of insurance plans including Medicare and Medicaid
  • High patient satisfaction ratings
  • Accessible location with climate-controlled walkways and shuttle services
  • Reputation for excellence and expertise of doctors
  • Offers advanced technology and equipment
  • Provides a variety of support services for patients and families
  • Integrated medical center
  • Multiple payment options and financial assistance available
  • Clean and newly renovated environment
Cons:
  • Waiting times for appointments can vary
  • Not all Medicare Advantage plans are accepted
  • Telemedicine services availability not specified

MD Anderson Cancer Center (Houston, TX)

Pros:
  • Exceptional medical staff
  • High-quality care
  • Compassionate and respectful environment
  • Efficient appointment scheduling
  • Personalized treatment options
  • Cutting-edge research and innovative therapies
  • Variety of support services
  • Advanced technology available
Cons:
  • Classrooms are not cleaned frequently
  • Restrooms are broken and smelly
  • Individual insurance plans on or off the marketplace in Texas (i.e., ACA plans) are not participating providers

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